Optimization of a new score function for the detection of remote homologs

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چکیده

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Optimization of a new score function for the detection of remote homologs.

The growth in protein sequence data has placed a premium on ways to infer structure and function of the newly sequenced proteins. One of the most effective ways is to identify a homologous relationship with a protein about which more is known. While close evolutionary relationships can be confidently determined with standard methods, the difficulty increases as the relationships become more dis...

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ژورنال

عنوان ژورنال: Proteins: Structure, Function, and Genetics

سال: 2000

ISSN: 0887-3585,1097-0134

DOI: 10.1002/1097-0134(20001201)41:4<498::aid-prot70>3.0.co;2-3